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1 Introduction SERS is a method that has been widely studied over the last decades. It is based on an interaction of the analyte and substrate surface (most typically plasmonic nanoparticles of Ag or Au) under laser irradiation. Under the laser beam, the optical field around nanoparticle or their aggregates can be strongly amplified due to localised surface plasmon resonance (LSPR), which results in subsequent enhancements of the analyte Raman signal.
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