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Articles by Rohan Samson

Sacubitril-Valsartan in Heart Failure: The Hard Sell of Spending More to Save Later

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By Le TH, Rohan Samson
| nlm.nih.gov
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Respite for 2-Dimensional Right Ventricular Imaging?

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By Rohan Samson
| circimaging.ahajournals.org
The complex geometry and structure of the right ventricular (RV) cavity make the assessment of RV function and volumes by 2-dimensional (2D) echocardiography arduous. Highly trabeculated endocardial border and bellows-like contractile pattern are not explicitly imaged by 2D echocardiography.1,2 Furthermore, the retrosternal position of the right ventricle hinders its visualization, and minimal changes in the angle of insonification affect RV chamber measurement and thereby, reproducibility.
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Clinical Phenotypes in Heart Failure With Preserved Ejection Fraction

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By Mark Cassidy Verified, Rohan Samson, Abhishek Jaiswal, Pierre V. Ennezat
| jaha.ahajournals.org
A novel paradigm in HFpEF associates comorbid conditions to an inflammatory state that increases LV stiffness and promotes HF. 71 The cellular and molecular mechanisms that lead from systemic inflammation to myocardial fibrosis (reduced nitric oxide bioactivity, cyclic guanosine monophosphate content, and protein kinase G) also promote arterial stiffening, with the endothelium being an essential component of vascular homeostasis.
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