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1 Introduction Pressure ulcers (PUs), also known as bedsores or decubitus ulcers, are localized areas of tissue necrosis that develop when soft tissue is compressed between a bony prominence and an external surface for a prolonged period [1]. PUs represent a major health care burden worldwide, affecting approximately 2.5 million patients annually in the United States alone, with treatment costs exceeding $11 billion per year [2, 3].
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