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Topics Publisher: PLoS One Availability: Non-RAND Year: 2025 Document Number: EP-71157 This publication is part of the RAND external publication series. Many RAND studies are published in peer-reviewed scholarly journals, as chapters in commercial books, or as documents published by other organizations. RAND is a nonprofit institution that helps improve policy and decisionmaking through research and analysis.
Importance Households have high burden of health care payments. Alternative financing approaches could reduce this burden for some households. Objective To estimate the distribution of household health care payments across income under health care reform policies. Design, Setting, and Participants Cross-sectional study with microsimulation used nationally representative data of the US population in 2030.
A carrier-based, immunogenic cell death (ICD)-eliciting platinum(IV) chemotherapeutic agent was synthesized via complexation between an axially derivatized Pt(IV)-tocopherol and hyaluronan (HA)–tocopherol nanocarrier. The resultant HA-Pt(IV) complex demonstrated antiproliferative activity and induced calreticulin translocation, an indicator of ICD, in murine and human head and neck cancer (HNC) cells.
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