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S. Flavin

As seen in: Color Research & Application
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Articles by S. Flavin

Guselkumab 对使用优特克单抗疗效不佳的银屑病患者的有效性和安全性:随机、双盲 III 期 NAVIGATE 试验结果

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By T. -F. Tsai, M. Song, J. Jiang, S. Li, L. Puig, R. G. Langley, S. Flavin, B. Randazzo, Y. Wasfi
| Color Research & Application Verified
Summary??????????,???????????????????(???????)???????? (IV) ??,??????????????????????????????????,??????????????????????????,?????????????,???? (IL)-12 ? IL-23????????,????????????????????????????????,???????????????????? IL-23 ??????????? IL-12 ???,guselkumab ????,???????? IL-23 ?? IL-12 ?????????,???????????,???????????????? NAVIGATE ???,871 ????????????????????????????? 16 ??,??????????,????????????????????? guselkumab ??,??? 44 ????? 16 ??? 40 ?,???????????????????(?? 4 ?)??,??
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Efficacy and safety of guselkumab in patients with psoriasis who have an inadequate response to ustekinumab: results of the randomized, double-blind, phase III NAVIGATE trial - Langley - 2018 - British Journal of Dermatology - Wiley Online Library

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By R. G. Langley, T. -F. Tsai, S. Flavin, M. Song, B. Randazzo, Y. Wasfi, J. Jiang, S. Li, L. Puig
| Color Research & Application Verified
Psoriasis is a chronic disease causing red and scaling skin lesions. Current treatments, especially biologics, which are either given by injection or intravenous infusion (IV), are very effective in the treatment of moderate to severe plaque psoriasis. However, most patients look to achieve clear skin, so there is room for improvement. One approved biologic, ustekinumab, blocks two of the body's internal proteins, interleukin (IL)-12 and IL-23.
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