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Background: Adoptive cell therapy (ACT) can induce objective clinical responses in solid tumors. However, its potential in colorectal cancer (CRC) remains poorly exploited. To this end, several questions need to be addressed: Can tumor-infiltrating lymphocytes (TIL) be isolated from CRC, including cryopreserved samples? Can the contamination by the gut microbiota be circumvented? Are CRC TIL similar to those expanded in melanoma trials?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.