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Sabrina Dinkel

As seen in: The Journal of Immunology
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Articles by Sabrina Dinkel

STAT3 Gain-of-Function Mutations Underlie Deficiency in Human Nonclassical CD16+ Monocytes and CD141+ Dendritic Cells

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By Daniel Korenfeld, Kate Roussak, Sabrina Dinkel, Tiphanie P. Vogel
| The Journal of Immunology Verified
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STAT3 Gain-of-Function Mutations Underlie Deficiency in Human Nonclassical CD16+ Monocytes and CD141+ Dendritic Cells

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By Daniel Korenfeld, Tiphanie P. Vogel, Kate Roussak, Sabrina Dinkel
| The Journal of Immunology Verified
Daniel Korenfeld, Kate Roussak, Sabrina Dinkel, Tiphanie P. Vogel, Henry Pollack, Joseph Levy, Jennifer W. Leiding, Joshua Milner, Megan Cooper and Eynav Klechevsky J Immunol October 15, 2021, ji2000841; DOI: https://doi.org/10.4049/jimmunol.2000841 Key Points STAT3 gain-of-function causes a novel disorder of dendritic cells and monocytes. STAT3 gain-of-function patients lack nonclassical monocytes and certain dendritic cells. STAT3 mutations cause altered dendritic cell differentiation.
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