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Articles by Sandra Martineau
RV-specific Targeting of Snai1 Rescues Pulmonary Hypertension-induced Right Ventricular Failure by Inhibiting EndMT and Fibrosis via LOXL2 Mediated Mechanism
Abstract Background: Pulmonary hypertension (PH)-induced right ventricular (RV) failure (PH-RVF) is a significant prognostic determinant of mortality and is characterized by RV hypertrophy, endothelial-to-mesenchymal transition (EndMT), fibroblast-to-myofibroblast transition (FMT), fibrosis, and extracellular matrix (ECM)-remodeling. Despite the importance of RV function in PH, the mechanistic details of PH-RVF, especially the regulatory control of RV EndMT, FMT, and fibrosis, remain unclear.
R-Crizotinib predisposes to and exacerbates pulmonary arterial hypertension in animal models
Charifa Awada, Yann Grobs, Wen-Hui Wu, Karima Habbout, Charlotte Romanet, Sandra Breuils-Bonnet, Eve Tremblay, Sandra Martineau, Roxane Paulin, Sébastien Bonnet, Steeve Provencher, François Potus, Olivier Boucherat European Respiratory Journal 2021 57: 2003271; DOI: 10.1183/13993003.03271-2020 Abstract This study demonstrates that R-crizotinib, a frontline therapy for lung cancer, predisposes to and exacerbates PH in animal models.
(R)-Crizotinib Predisposes To and Exacerbates Pulmonary Arterial Hypertension in Animal Models
Charifa Awada, Yann Grobs, Wen-Hui Wu, Karima Habbout, Charlotte Romanet, Sandra Breuils-Bonnet, Eve Tremblay, Sandra Martineau, Roxane Paulin, Sébastien Bonnet, Steeve Provencher, François Potus, Olivier Boucherat European Respiratory Journal 2021; DOI: 10.1183/13993003.03271-2020 Footnotes This manuscript has recently been accepted for publication in the ERJ Open Research. It is published here in its accepted form prior to copyediting and typesetting by our production team.
CD34 regulates the skeletal muscle response to hypoxia
Authors Authors and affiliations Mélissa Pagé Catherine Maheux Anick Langlois Julyanne Brassard Émilie Bernatchez Sandra Martineau Cyndi Henry Marie-Josée Beaulieu Ynuk Bossé Mathieu C. Morissette Richard Debigaré Marie-Renée Blanchet Rapid Communication First Online: 20 June 2019 Abstract Chronic obstructive pulmonary disease (COPD) can sometimes be associated with skeletal muscle atrophy.
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