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Articles by São Julião
A multi-centre randomized controlled trial investigating Consolidation Chemotherapy with and without oxaliplatin in distal rectal cancer and Watch & Wait | BMC Cancer | Full Text
Definitions Definition of cCR Endoscopic: white scar, teleangiectasia, absence of ulceration and/or mass [6]. Clinical: no irregularity, firm area with minor induration [6]. Radiological: mrTRG1: fibrosis with low signal intensity seen on T2 weighted images replacing the primary tumor; no restricted diffusion on diffusion weighted images; no nodes with border irregularity or mixed signal intensity; no EMVI [23,24,25,26].
Near-complete response following neoadjuvant therapy in rectal cancer: resect now?
Organ preservation has become an attractive alternative treatment strategy for patients with rectal cancer. Patients who achieve all strict and standardized criteria for a cCR appear to be managed safely without immediate surgery and close surveillance (watch and wait)1. This well defined group of patients has a long-term risk of developing local regrowth of 30 per cent, and distant metastases of 12 per cent, both in retrospective and prospective cohort studies2,3.
Near-complete response following neoadjuvant therapy in rectal cancer: resect now?
Organ preservation has become an attractive alternative treatment strategy for patients with rectal cancer. Patients who achieve all strict and standardized criteria for a cCR appear to be managed safely without immediate surgery and close surveillance (watch and wait)1. This well defined group of patients has a long-term risk of developing local regrowth of 30 per cent, and distant metastases of 12 per cent, both in retrospective and prospective cohort studies2,3.
The Risk of Distant Metastases in Patients With Clinical... : Diseases of the Colon & Rectum
1 Colorectal Surgery, Digestive Department, Champalimaud Foundation, Lisbon, Portugal 2 Colorectal Surgery Division, Angelita and Joaquim Gama Institute, São Paulo, Brazil 3 Department of Surgical Oncology, Colorectal Surgery Division, Hospital Beneficencia Portuguesa, São Paulo, Brazil 4 Colorectal Surgery Division, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil 5 Manchester Cancer Research Centre, National Institute of Health and Research Manchester Biomedical Research Centre, Division of...
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