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Sarah E. Gullbrand

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Articles by Sarah E. Gullbrand

Tension-activated nanofiber patches delivering an anti-inflammatory drug improve repair in a goat intervertebral disc herniation model

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By Ana P. Peredo, Yasutaka Yamada, Shuaiya Ma, Sarah E. Gullbrand
| Science Magazine Verified
Tension-activated nanofiber patches delivering an anti-inflammatory drug improve repair in a goat intervertebral disc herniation model Ana P. Peredo https://orcid.org/0000-0001-8383-039X, Sarah E. Gullbrand https://orcid.org/0000-0001-7806-6606, [...] , Chet S. Friday https://orcid.org/0009-0008-2628-5063, Brianna S. Orozco https://orcid.org/0009-0003-3271-2678, [...] , Bijan Dehghani https://orcid.org/0000-0002-3074-1454, Austin C. Jenk https://orcid.org/0000-0003-3481-1234, Edward D.
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Tension-activated nanofiber patches delivering an anti-inflammatory drug improve repair in a goat intervertebral disc herniation model

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By Ana P. Peredo, Yasutaka Yamada, Shuaiya Ma, Sarah E. Gullbrand
| Science Magazine Verified
Published In Science Translational Medicine Volume 15 | Issue 722 November 2023 Article versions Submission history Received: 18 October 2022 Accepted: 26 October 2023 Permissions Request permissions for this article.
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Long-term mechanical function and integration of an implanted tissue-engineered intervertebral disc

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By Sarah E. Gullbrand, Beth G. Ashinsky, Edward D. Bonnevie, Dong Hwa Kim
| Science Magazine Verified
Intervertebral disc degeneration causes back and neck pain, sometimes necessitating disc fusion surgery. Although fusion may alleviate symptoms, it does not address the underlying cause of degeneration. As an alternative to fusion, Gullbrand and colleagues developed tissue-engineered discs for disc replacement by sandwiching hydrogel and polymer materials seeded with cartilage or mesenchymal stem cells between acellular polymer endplates.
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