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Articles by Serena Zheng
Neoadjuvant modified FOLFIRINOX plus nivolumab in borderline-resectable pancreatic ductal adenocarcinoma: a pilot phase 1 trial - Nature Communications
Abstract Chemotherapy and immune checkpoint inhibitor combinations have failed to improve survival in pancreatic ductal adenocarcinoma (PDAC), except in rare microsatellite instability-high cases; most studies focused on advanced disease. Here, we present clinical and translational results from a single-arm, prospective phase 1b/2 investigator-initiated study (NCT03970252) evaluating neoadjuvant modified FOLFIRINOX (mFFX) plus nivolumab in patients with borderline-resectable PDAC.
Ampullary Adenocarcinoma-Advancing Prognostication and Personalized Treatment
Ampullary Adenocarcinoma—Advancing Prognostication and Personalized Treatment Genome-Derived Ampullary Adenocarcinoma Classifier and Postresection Prognostication Brett L. Ecker, MD; Kenneth Seier, MS; Austin M. Eckhoff, MD; Gabriella N. Tortorello, MD; Peter J. Allen, MD; Vinod P. Balachandran, MD; Nicola Blackburn, PhD; Michael I. D’Angelica, MD; Ronald P. DeMatteo, MD; Daniel G. Blazer III, MD; Jeffrey A. Drebin, MD, PhD; William E. Fisher, MD; Danielle Fortuna, MD; Anthony J.
Cell State and Cell Type: Deconvoluting Circulating Tumor Cell Populations in Liquid Biopsies by Multi-Omics
Abstract : Simple Summary In addition to millions of normal red and white blood cells, the blood of cancer patients contains a variety of very rare cell types associated with the tumor. A simple blood draw or ‘liquid biopsy’ can, thus, provide important information about the state of the disease no matter where it exists in the body.
Outcomes of Patients with Positive Interim Positron Emission Tomography (PET) Continuing ABVD in the Clinical Setting
Abstract : Simple Summary This study aimed to highlight limitations in the use of interim PET (iPET) for treatment decisions and prognostication in the frontline management of Hodgkin’s lymphoma. It reinforces the observation from the ECHELON-1 study that outcomes of patients with a positive interim PET who nonetheless continue treatment with ABVD are not as dismal as previously described.
Bordeaux plunges to record low in Liv-ex Power 100 ranking
While Burgundy and Champagne continuously build on last year’s momentum, 2022 Liv-ex Power 100 ranking saw Bordeaux further losing attractiveness with no single wine from the region on the top 10 list for the first time, says Liv-ex. 2022 marks another tough year for Bordeaux.
Hepatitis C‐positive Black patients develop hepatocellular carcinoma at earlier stages of liver disease and present with a more aggressive phenotype
Original Article Umut Sarpel MD Corresponding Author umut.sarpel@mountsinai.org Division of Surgical Oncology, Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, New York Corresponding Author: Umut Sarpel, MD, Department of Surgery, Box 1259, The Mount Sinai Medical Center, 1 Gustave L. Levy Place, New York, NY 10029‐6574 (umut.sarpel@mountsinai.org). Search for more papers by this author See editorial on pages 1‐2, this issue.
An Accessibility Checklist for Designers and Developers
How to create accessible UI, and why it matters Illustration by Lizzie Buehler Accessibility: (noun) the qualities that make an experience open to all Accessible design is good design — an accessible user interface (UI) opens experiences to a wider range of users and improves experiences for existing users. That’s the beauty of designing with all abilities in mind — it benefits everyone, not just those with limited vision, hearing, or mobility.
Cost & Aid
Our aid program is designed to encourage all qualified students — regardless of financial circumstances — to consider applying for admission to Princeton. Reflected in Princeton’s financial aid program is our commitment to equality of opportunity. Princeton admission is need-blind — there is no disadvantage in the admission process for financial aid applicants. This ensures a continued and growing enrollment of a diverse group of students from all socioeconomic backgrounds.
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