Non‐restorative sleep is a hallmark symptom of chronic fatigue syndrome/myalgic encephalomyelitis. However, little is known about self‐reported sleep disturbances in these subjects. This study aimed to assess the self‐reported sleep quality and its impact on quality of life in a Spanish community‐based chronic fatigue syndrome/myalgic encephalomyelitis cohort. A prospective cross‐sectional cohort study was conducted in 1,455 Spanish chronic fatigue syndrome/myalgic encephalomyelitis patients.