1 Introduction Periodontal diseases like periodontitis are highly prevalent and destroy structures such as alveolar bone, cementum, and periodontal ligament (PDL) that support the teeth (Albandar 2005; Hajishengallis 2015; Ebersole et al. 2018; Kuboniwa et al. 2017; Tsukasaki et al. 2018; Ammar et al. 2018; Xu et al. 2019). This can eventually lead to tooth loss and complications with chewing, nutrition intake, and esthetics (Xu et al. 2019; Pihlstrom, Michalowicz, and Johnson 2005; Nasajpour et al.
