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Shaojin Lu

As seen in: Wiley Online Library, Royal Society of Chemistry
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Articles by Shaojin Lu

Hypoxia-Activated Paclitaxel Prodrug Combined with Dimeric Indocyanine Green for STING Activation and Reinvigorated Cancer Treatment

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By Xiujuan Xiang, Shaojin Lu, Hui Wen
| dx.doi.org
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Paclitaxel Prodrug Enables Glutathione Depletion to Boost Cancer Treatment

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By Biyou Zhang, Shiyu Zhou, Shaojin Lu, Xiujuan Xiang
| dx.doi.org
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Ferric Ion‐Driven Chlorin E6 Nanoparticles: Simple and Effective Multimodal Theranostics

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By Qing Pei, Shiyu Zhou, Shaojin Lu, Dengyuan Hao
| Wiley Online Library Verified
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202304205-sup-0001-SuppMat.pdf1.3 MB Supporting Information References 1a) , , , , , , , , , , Chem. Soc. Rev. 2020, 49, 8065; b) , World J. Surg. 1983, 7, 700. 2, , , , , Chem. Eng. J. 2023, 457, 141017. 3a) , , , Lancet Oncol. 2004, 5, 497; b) , , , , , , , , Adv. Funct. Mater. 2021, 31, 2103714; c) , , , Nat. Rev. Cancer 2003, 3, 380. 4, , , , Chem. Soc. Rev. 2018, 47, 4258. 5, , , , , , Chem. Rev.
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Ferric Ion‐Driven Chlorin E6 Nanoparticles: Simple and Effective Multimodal Theranostics

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By Qing Pei, Shiyu Zhou, Shaojin Lu, Dengyuan Hao
| pericles.pericles-prod.literatumonline.com
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202304205-sup-0001-SuppMat.pdf1.3 MB Supporting Information References 1a) , , , , , , , , , , Chem. Soc. Rev. 2020, 49, 8065; b) , World J. Surg. 1983, 7, 700. 2, , , , , Chem. Eng. J. 2023, 457, 141017. 3a) , , , Lancet Oncol. 2004, 5, 497; b) , , , , , , , , Adv. Funct. Mater. 2021, 31, 2103714; c) , , , Nat. Rev. Cancer 2003, 3, 380. 4, , , , Chem. Soc. Rev. 2018, 47, 4258. 5, , , , , , Chem. Rev.
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A Paclitaxel Prodrug with Copper Depletion for Combined Therapy toward Triple-Negative Breast Cancer

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By Dengyuan Hao, Qian Meng, Chaonan Li, Shaojin Lu
| dx.doi.org
Tuning the content of copper is of great significance for the treatment of cancer and neurodegenerative diseases. Herein, we synthesized a redox-responsive paclitaxel (PTX) prodrug by conjugating PTX with a copper chelator through a disulfide bond. The as-fabricated prodrug (PSPA) showed specific chelation toward copper ions and could assemble with distearoyl phosphoethanolamine-PEG2000 to form stable nanoparticles (PSPA NPs) in aqueous media.
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Fluorinated Paclitaxel Prodrugs for Potentiated Stability and Chemotherapy

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By Bowen Jiang, Chaonan Li, Dengyuan Hao, Shaojin Lu
| Royal Society of Chemistry Verified
Fluorinated Paclitaxel Prodrugs for Potentiated Stability and Chemotherapy The robust colloidal stability is an essential prerequisite for the effective drug delivery. Herein, a series of fluorinated paclitaxel prodrugs bridged with redox-responsive linkages were synthesized, and the effect of fluorination on assembly behaviors and physiological stability was investigated.
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