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Abstract Endemic human coronaviruses (HCoVs), such as HCoV-HKU1, account for ~30% of common colds each year and can cause serious upper and lower respiratory infections, yet no licensed vaccines or therapeutic antibodies target HCoVs. Despite being endemic to the human population, little is known about the antigenic landscape of HCoV-HKU1.
KG, JAM, DFR, and BGH are named as inventors on a patent application relating to this work. IAA received the Swiss Fellowship Gilead research grant and received a travel grant from Gilead Sciences (paid to the institution).
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