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Highlights • SSEP monitoring alone is highly specific but weakly sensitive for postoperative neurologic deficit following cervical spine surgery. • Patients with new postoperative neurologic deficits were nearly 27 times more likely to have had significant intraoperative SSEP change. • Loss of SSEP signals and mostly notably, irreversible SSEP changes seem to indicate a much higher risk of injury than reversible SSEP changes.
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