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Articles by Shuning Lv
Wnt induces FZD5/8 endocytosis and degradation and the involvement of RSPO-ZNRF3/RNF43 and DVL
eLife Assessment This study presents important findings demonstrating that the internalization and degradation of FZD5 and FZD8, two of the ten Frizzled proteins, are WNT dependent and do not involve DVL. The evidence supporting the claims of the authors is convincing. This research will be of interest to biologists specializing in Wnt signaling, cancer, and regenerative medicine.
Antiferroelectric SnO2 Network with Amorphous Surface for Electrochemical N2 Fixation
Conflict of Interests The authors declare no conflict of interest. Supporting Information Filename Description anie202515222-supp-0001-SuppMat.docx6.7 MB Supporting Information References 1, , , , , , , , , Nat. Catal. 2018, 1, 490–500. 2, , , , , , Nat. Catal. 2019, 2, 290–296. 3, , , , , , , Angew. Chem. Int. Ed. 2025, 64, e202416878. 4, Nat. Catal. 2019, 2, 377–380. 5, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , et al., Science 2018, 360, eaas9793. 6, , , Mater. Today Catal 2025, 9, 100103.
Wnt specifically induces FZD5/8 endocytosis and degradation and the involvement of RSPO-ZNRF3/RNF43 and DVL
Abstract Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ligases ZNRF3 and RNF43 promote the endocytosis and degradation of FZD receptors to inhibit Wnt signaling, and their function is antagonized by R-spondin (RSPO) proteins.
Amorphous Bismuth-Tin Oxide Nanosheets with Optimized C-N Coupling for Efficient Urea Synthesis
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Am. Chem. Soc. 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
Amorphous Bismuth-Tin Oxide Nanosheets with Optimized C-N Coupling for Efficient Urea Synthesis
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Am. Chem. Soc. 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
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