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Abstract Osteoclastogenesis requires precise coordination between mitochondrial bioenergetics and anabolic programs, yet the underlying mechanisms remain unclear. Here, we identify the mitochondrial citrate carrier (CIC, encoded by SLC25A1) as a crucial link that couples mitochondrial bioenergetics to glutathione (GSH)-dependent redox regulation during osteoclastogenesis.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
