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Abstract Alzheimer’s disease (AD) is characterized by progressive neurodegeneration and cognitive decline, yet most candidate therapies targeting amyloid-β have failed to robustly modify disease progression, underscoring an incomplete mechanistic understanding.
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description anie74604-sup-0001-SuppMat.docx4.5 MB Supporting File: anie74604-sup-0001-SuppMat.docx.
Abstract and Introduction Abstract Background: Acute kidney injury (AKI) is a common and severe complication of cardiac surgery with cardiopulmonary bypass (CPB). This study aimed to establish a model to predict the probability of postoperative AKI in patients undergoing cardiac surgery with CPB. Methods: We conducted a retrospective, multicenter study to analyze 1082 patients undergoing cardiac surgery under CPB.
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