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Editor’s summary Narcolepsy is characterized by excessive sleepiness and episodes of cataplexy, a REM sleep–related loss of muscle tone. The regulation of body temperature and wakefulness is integrated in the hypothalamic Hcrt (hypocretin/orexin) and MCH (melanin-concentrating hormone) systems, but whether cataplexy and REM sleep share thermomodulatory mechanisms remains elusive. Here, Viberti et al.
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