Int J Med Sci 2021; 18(7):1592-1599. doi:10.7150/ijms.52405 Research Paper Can Yao1*, Lingwei Wang1*, Fei Shi2 , Rongchang Chen1 , Binbin Li2, Wenwen Liu2, Mengjie Feng1, Sinian Li1 1. Key Laboratory of Shenzhen Respiratory Diseases, Institute of Shenzhen Respiratory Diseases, Shenzhen People's Hospital (The First Affiliated Hospital of Southern University of Science and Technology, The Second Clinical Medical College of Jinan University), Shenzhen, Guangdong, China. 2.