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1 Introduction Metastatic castration-resistant prostate cancer (mCRPC) remains largely unresponsive to multiple treatment interventions despite clinical advancements, although the overall fatality rate arising from prostate cancer has declined in developed nations [1]. Alarmingly, a global rise in prostate cancer incidence and its progression towards mCRPC is being observed [2].
Abstract Porphyromonas gingivalis, a gram-negative, bacterium interacts favourably with host subgingival biofilms to cause adult tooth decay and loss. Consequently, the host is infested with an uncontrollable microbial community and a compromised immune system, ultimately leading to tissue damage and bone resorption. P.
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