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Articles by Soyun Lee
Breath volatiles reflect diabetic gastroparesis and its recovery by activating Na v 1.8-expressing neurons in mice
Abstract Patients with diabetic gastroparesis (DG) experience chronic, challenging symptoms and currently lack effective treatment options. This study examined whether activating Nav1.8-expressing neurons could improve gastric motility and whether volatile organic compounds (VOCs) in exhaled breath could serve as non-invasive indicators of disease status and treatment response.
Engineering Hollow‐Structured Carbon Framework to Facilitate High‐Sulfur‐Content Encapsulation for Lithium‐Sulfur Batteries
1 Introduction The increasing demand for large-scale applications such as electric vehicles and portable electronic devices necessitates high-capacity and high-energy-density energy storage systems.[1-5] At the same time, competition to reduce battery costs is becoming ever more intense, prompting the search for alternatives beyond conventional lithium-ion batteries (LIBs).[6-9] Lithium-sulfur batteries (LSBs) have emerged as one of the most promising next-generation systems due to their...
Gold(I)−Catalyzed Synthesis of Cyclic Sulfamides via an Intramolecular Dehydrative Amination of Allylic Alcohols: A Strategy for 1,3‐Diamine Synthesis
Cyclic sulfamides represent crucial structural motifs in a broad spectrum of biologically active compounds. These distinctive frameworks are integral to compounds exhibiting diverse pharmacological effects, such as HIV inhibition,1 serine protease inhibition,2 modulation of serotonin receptor agonism/antagonism,3 inhibition of 11β-hydroxysteroid dehydrogenase 1,4 and antiviral effects.5 In addition to their biological significance, cyclic sulfamides demonstrate considerable synthetic utility.
Targeting EGFR/PI3K/AKT/mTOR Signaling in Hepatocellular Carcinoma
1. Introduction Liver cancer presents a significant global health challenge due to its rising incidence and mortality rates. According to the World Health Organization, liver cancer accounted for approximately 800,000 deaths, positioning it as the fourth leading cause of cancer-related mortality [1]. Liver cancer comprises a heterogeneous group of malignant tumors with varying histologic characteristics and poor prognoses.
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