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1 INTRODUCTION Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease associated with airway obstruction that results in respiratory symptoms such as difficulty in breathing, shortness of breath, wheezing, and chest tightness.
INTRODUCTION Influenza is a significant contributor to morbidity, mortality, and health care expenditures in the United States. Although the acute infection is generally self-limited, preliminary burden of illness estimates for the 2019-2020 influenza season from the Centers for Disease Control and Prevention (CDC) show that influenza was responsible for 16.1 million excess outpatient visits, 380,209 excess hospitalizations, and 20,342 deaths1.
Asthma is a complex respiratory disorder characterized by marked heterogeneity in individual patient disease triggers and response to therapy. Several asthma phenotypes have now been identified, each defined by a unique interaction between genetic and environmental factors, including inflammatory, clinical and trigger-related phenotypes. Endotypes further describe the functional or pathophysiologic mechanisms underlying the patient's disease.
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