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Iridium(iii)-based minor groove binding complexes as DNA photocleavage agents† Transition metal complexes containing the qtpy ligand (2′:4,4′′:4′,4′′′-quaterpyridyl) are known to be DNA intercalators or minor groove binders. In this study, new tricationic iridium(III) complexes of qtpy are reported. Both [Ir(bpy)2(qtpy)]3+1 and [Ir(phen)2(qtpy)]3+2 display good water solubility as chloride salts.
Sub-Saharan Africa . In sub-Saharan Africa, there are 626,400 new cancer cases each year and 447,700 cancer deaths. It is estimated that cancer incidence in Sub-Saharan Africa will rise by 85% in the next fifteen years due to population ageing. Each year, cancer claims the lives of 72,000 Nigerians, with an estimated 102,000 new cases diagnosed. The most common types of cancer in Nigeria are breast and cervical cancer, accounting for ~50.3% of all cancer cases.
Stephen Aderinto Published 29 December 2021 Sub-Saharan Africa . In sub-Saharan Africa, there are 626,400 new cancer cases each year and 447,700 cancer deaths. It is estimated that cancer incidence in Sub-Saharan Africa will rise by 85% in the next fifteen years due to population ageing. Each year, cancer claims the lives of 72,000 Nigerians, with an estimated 102,000 new cases diagnosed.
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