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ABSTRACT Introduction Cervical dystonia (CD) causes involuntary movements and postures of the head, neck, and shoulders, as well as nonmotor symptoms including pain, mood, and sleep dysfunction, and impacts quality of life. The first-line treatment for CD is botulinum neurotoxin (BoNT) injections. Areas covered The clinical presentation and diagnosis of CD, as well as where BoNT resides in the treatment landscape, is reviewed first.
The treatment of Parkinson’s disease (PD) has been dominated by dopamine replacement therapy for over 60 years. Following the introduction of levodopa in the 1960s, a range of dopamine agonist drugs (e.g. apomorphine, bromocriptine, cabergoline, pergolide, ropinirole, pramipexole, rotigotine) were added to (and some subsequently removed from) the PD armamentarium [Citation1, , , et al.
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