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References Schwartz J, Winters JL, Padmanabhan A, Balogun RA, Delaney M, Linenberger ML, et al. Guidelines on the use of therapeutic apheresi s inclinical Practice—Evidence-Based approach from thewriting committee of the American society forapheresis: the sixth special issue. J Clin Apher. 2013;28(3):145–284. PubMed Google Scholar Williams ME, Balogun RA. Clinical Journal of the American Society of Nephrology. Volume 9. American Society of Nephrology; 2014. pp. 181–90.
This study was approved by the ethics committee (Comitê de Ética no Uso de Animais - CEUA) of the Faculty of Veterinary Medicine and Animal Science, UNESP (protocol number 0084/2021). The animals included in this study were selected during a visit to the Veterinary Nephrology and Urology Service at the Small Animal Medical Clinic of the Veterinary Hospital of the Faculty of Veterinary Medicine and Animal Science, UNESP in Botucatu, São Paulo.
Hemangiosarcoma is a rapidly growing and aggressive malignant neoplasm, demonstrating significant metastatic potential due to its vascular association [1]. In dogs, the primary site of development is typically the spleen, followed by other locations such as subcutaneous tissue, dermis, liver, and right atrium [2,3,4,5]. Less common sites include the retroperitoneum, reproductive system, lung, and urinary system [6,7,8,9].
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