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Abstract Paediatric chronic kidney disease (CKD) is a progressive and life-altering condition that is associated with substantial comorbidities, reduced life expectancy and considerable burdens on children, families and health care systems. Despite advances in supportive medical management, therapeutic development in paediatric CKD remains sparse.
Early diagnosis of rare kidney diseases has profound implications for patients in terms of access to treatment, disease trajectory and the identification of affected relatives. The innovative and collaborative approach taken by the global Alport community has delivered a sustainable global network that has advanced treatments and knowledge and offers insights that are relevant to the entire nephrology community.
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