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The Reagent Collaboration Network (Reclone) seeks to address the global asymmetry in research and development in biotechnology across the Global South through open sharing of biomaterials, protocols and knowledge. The end goal is to build an international community enabling more sustainable, equitable and decentralized reagent manufacturing. The initiative works through regional distribution hubs and nodes to provide local access to resources and expertise in reagent manufacturing.
Abstract Infectious pancreatic necrosis virus (IPNv) poses a significant threat to the global salmon farming industry, causing high mortality and economic losses. Given the limitations of traditional antibody therapies in aquaculture, we explored the development of nanobodies targeting the VP2 protein of IPNv. We developed a novel nanobody library generation method using a streamlined assembly protocol based on Type IIS restriction enzymes.
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