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Abstract: Objective To explore the role and possible mechanism of a disintegrin and metalloproteinase 10 (ADAM10) in osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) and tibial fracture union. Methods BMSCs of SD rats were cultured, stably transfected with a negative control (NC) shRNA pGFP-V-RS vector, and divided into sh-NC and sh-NC+DMSO groups.
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