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Picking the tyrosine-lock: chemical synthesis of the tyrosyl-DNA phosphodiesterase I inhibitor recifin A and analogues The peptide recifin A is the inaugural member of the structurally intriguing new fold referred to as a tyrosine-lock. Its central four stranded β-sheet is stabilized by a unique arrangement in which three disulfide bonds and their interconnecting backbone form a ring that wraps around one of the strands, resulting in a Tyr side chain being buried in the molecular core.
Juniata College received a $30,000 grant from It’s On Us PA. Within the grant, there are some objectives for the College to follow and mini-grants for faculty. It’s On Us PA is the Pennsylvania branch of the It’s On Us campaign launched by former President Barack Obama and former Vice President Joe Biden. Pennsylvania was the first state to start its own branch of the organization.
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