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Abstract To evaluate whether genetic liability to higher bone mineral density (BMD) is associated with spinal stenosis and primary lumbar decompression surgery. We integrated two-sample Mendelian randomization (MR), multivariable MR, MRlap, reverse MR, and longitudinal UK Biobank analyses. The primary exposure was UK Biobank heel estimated BMD (eBMD); lumbar spine and total body DXA BMD were evaluated as sensitivity exposures.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
