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Objective The objective of this study was to examine associations between umbilical cord mitochondrial DNA copy number (mtDNAcn) and adiposity across childhood. Methods In a prospective birth cohort of Dominican and African American children from New York City, New York (1998–2006), mtDNAcn was measured in cord blood. Children (N = 336) were evaluated for their height, weight, and bioimpedance at age 5, 7, 9, and 11 years.
Associations between maternal asthma and atopy and breast milk-derived extracellular vesicle microRNA profiles in the PRISM pregnancy cohort Abstract BACKGROUND AND AIM: Maternal asthma is associated with adverse infant and child health including preterm birth and respiratory outcomes. Breast milk contains extracellular vesicle (EV)-encapsulated microRNAs, a form of mother-infant biochemical communication and may represent one pathway by which maternal health impacts child development and health.
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