08-18-2020 10:07 AM Endpoint detection and response (EDR) in block mode is a new capability in Microsoft Defender Advanced Threat Protection (Microsoft Defender ATP) that turns EDR detections into blocking and containment of malicious behaviors. This capability uses Microsoft Defender ATP’s industry-leading visibility and detection capability to provide an additional layer of post-breach blocking of malicious behavior, malware, and other artifacts that your primary antivirus solution might miss.