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Introduction – Why? Pathophysiologic Background of Chronic Ventilatory Failure Chronic obstructive pulmonary disease (COPD) is one of the most prevalent chronic diseases in Western countries. The disease progresses variably and can result in respiratory failure. Type I respiratory failure with severe hypoxaemia can be qualifying for Long-term oxygen treatment (LTOT). Therapeutic effects of LTOT are improved dyspnoea, exercise tolerance, and health-related quality of life (HRQL) [1].
Impact of alpha 1-antitrypsin deficiency and prior augmentation therapy on patients' survival after lung transplantation Anton Conrad, Sabina Janciauskiene, Thomas Köhnlein, Jan Fuge, Philipp Ivanyi, Igor Tudorache, Jens Gottlieb, Tobias Welte, Thomas Fuehner European Respiratory Journal 2017 50: 1700962; DOI: 10.1183/13993003.00962-2017
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