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Disentangling Temporal and Rate Codes in the Primate Somatosensory Cortex Thierri Callier, Thomas Gitchell, Michael A. Harvey, Sliman J. Bensmaia Journal of Neuroscience 18 September 2024, 44 (38) e0036242024; DOI: 10.1523/JNEUROSCI.0036-24.2024
Abstract Millisecond-scale temporal spiking patterns encode sensory information in the periphery, but their role in cortex remains controversial. The sense of touch provides a window into temporal coding because tactile neurons often exhibit precise, repeatable, and informative temporal spiking patterns. In somatosensory cortex (S1), responses to skin vibrations exhibit phase-locking that faithfully carries information about vibratory frequency.
Caffeine, one of the most commonly consumed psychoactive substances in the world, has long been known to alter neurological functions, such as alertness, attention, and memory. Despite caffeine's popularity, systematic investigations of its effects on synaptic plasticity in the brain are still lacking.
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