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Metabolism Abstract The two closely related RabGTPase-activating proteins (RabGAPs) TBC1D1 and TBC1D4 play a crucial role in the regulation of GLUT4 translocation in response to insulin and contraction in skeletal muscle.
Hypoxia in Combination With Muscle Contraction Improves Insulin Action and Glucose Metabolism in Human Skeletal Muscle via the HIF-1? Pathway Sven W. Görgens, Tim Benninghoff, Kristin Eckardt, Christian Springer, Alexandra Chadt, Anita Melior, Jakob Wefers, Andrea Cramer, Jørgen Jensen, Kåre I. Birkeland, Christian A. Drevon, Hadi Al-Hasani, Jürgen Eckel Diabetes Nov 2017, 66 (11) 2800-2807; DOI: 10.2337/db16-1488
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