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INTRODUCTION Long-term opioid use has been associated with elevated non-fatal and fatal overdose risks. Comorbidity and polypharmacy may elevate overdose risk among patients who inject drugs [1]. In England and Wales, almost 81% of deaths that involved benzodiazepines, gabapentinoids (gabapentin, pregabalin) and Z-drugs (zopiclone, zaleplon, zolpidem) also involved opioids.
We read with interest the study by Natasa Gisev and colleagues, 1 Gisev N Bharat C Larney S The effect of entry and retention in opioid agonist treatment on contact with the criminal justice system among opioid-dependent people: a retrospective cohort study. which provides further robust evidence for the effectiveness of opioid agonist treatment (OAT) in ameliorating the harm associated with opiate users' criminal offending.
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