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3.3. Unforeseen Consequences of a New Dosage Form: Slow Release Morphine as a palliation medication survived the ‘opiaphobia’ and ‘morphinophobia’ which continued to circulate in pain specialist quarters in America and Europe [,,,].
1. Introduction We investigate how to apply the theoretical understanding of (search) tasks and information seeking on the practical development of search engines. A growing body of scientific work is investigating how a user’s search tasks affect their information seeking (e.g., [1,2,3]).
A fertile ground for high-priced drugs has been created by changes in drug life-cycle dynamics, the unintended effects of patent legislation, government policy measures and orphan drug programs. There is an urgent need for regulatory reform to curtail prices and safeguard equitable access to innovative medicines.
In their recent News & Views article (Sustainability and affordability of cancer drugs: a novel pricing model. Nat. Rev. Clin. Oncol. 15, 405–406 (2018))1, Uyl-De Groot and Löwenberg outline a new universal algorithm for setting the price of new drugs in oncology. Their ambitious proposal is intended to standardize a complicated and fragmented pricing process. The international drug market is dynamic and diverse2.
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