Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Articles by Torben Sigsgaard
Artificial intelligence in asthma health literacy: a comparative analysis of ChatGPT versus Gemini
Abstract Background Asthma is a complex and heterogeneous chronic disease affecting over 300 million individuals worldwide. Despite advances in pharmacotherapy, poor disease control remains a major challenge, necessitating innovative approaches to patient education and self-management. Artificial intelligence driven chatbots, such as ChatGPT and Gemini, have the potential to enhance asthma care by providing real-time, evidence-based information.
Erratum for the Research Article “Fast growth of single-crystal covalent organic frameworks for laboratory x-ray diffraction” by J. Han et al.
During the revision of the Research Article “Fast growth of single-crystal covalent organic frameworks for laboratory x-ray diffraction” (1 March 2024, p. 1014), an independent research group, Yu et al., reported the fast growth of a large-sized (up to 450 μm) single-crystal covalent organic framework within 5 days [B. Yu et al., Nat. Chem. 16, 114 (2024)]. Yu et al.’s paper supports the Han et al. Research Article’s finding of fast growth of single-crystal covalent organic frameworks. The Yu et al.
Erratum for the Research Article “Rational design of Lewis base molecules for stable and efficient inverted perovskite solar cells” by C. Li et al.
eLetters is a forum for ongoing peer review. eLetters are not edited, proofread, or indexed, but they are screened. eLetters should provide substantive and scholarly commentary on the article. Embedded figures cannot be submitted, and we discourage the use of figures within eLetters in general. If a figure is essential, please include a link to the figure within the text of the eLetter. Please read our Terms of Service before submitting an eLetter.
Erratum for the Report “Chronic lymphocytic inflammation specifies the organ tropism of prions” by M. Heikenwalder et al.
Erratum for the Report “Chronic lymphocytic inflammation specifies the organ tropism of prions” by M. Heikenwalder et al. Upon review of supplemental fig. S4 in “ Chronic lymphocytic inflammation specifies the organ tropism of prions ” (18 February 2005), it has come to the authors’ attention that brain histological images had been erroneously duplicated from one genotype (NODB10), presented in supplemental fig. S4F, to another genotype (wild-type) in supplemental fig. S4D.
Carbon quaternization of redox active esters and olefins by decarboxylative coupling
Research Article ORGANIC CHEMISTRY Xu-cheng Gan https://orcid.org/0000-0001-7404-3087, Benxiang Zhang https://orcid.org/0009-0009-6787-2288, [...] , Nathan Dao https://orcid.org/0000-0003-4116-491X, Cheng Bi https://orcid.org/0000-0002-9332-9918, [...] , Maithili Pokle, Liyan Kan https://orcid.org/0009-0009-3986-5910, Michael R. Collins https://orcid.org/0000-0001-7799-1664, Chet C. Tyrol https://orcid.org/0009-0000-0121-8544, Philippe N.
HD-Zip proteins modify floral structures for self-pollination in tomato
Research Article PLANT SCIENCE Minliang Wu https://orcid.org/0000-0002-5126-1740, Xinxin Bian https://orcid.org/0000-0001-6847-6521, [...] , Benben Huang https://orcid.org/0000-0001-6868-1154, Yadi Du https://orcid.org/0009-0004-5839-1662, [...] , Shourong Hu https://orcid.org/0009-0006-5036-1885, Yanli Wang, Jingyuan Shen, and Shuang Wu https://orcid.org/0000-0003-1913-8125 wus@fafu.edu.cn+5 authors +3 authors fewerAuthors Info & Affiliations Editor’s summary Self-pollinating plants are...
De novo design of drug-binding proteins with predictable binding energy and specificity
Research Article PROTEIN DESIGN Lei Lu https://orcid.org/0000-0001-7097-1505, Xuxu Gou https://orcid.org/0000-0003-2318-778X, [...] , Sophia K. Tan https://orcid.org/0000-0002-6181-7810, Samuel I.
Prophage terminase with tRNase activity sensitizes Salmonella enterica to oxidative stress
Research Article MICROBIOLOGY Siva Uppalapati https://orcid.org/0000-0002-4743-7248, Sashi Kant https://orcid.org/0000-0002-9015-8383, [...] , Lin Liu, Ju-Sim Kim https://orcid.org/0000-0002-4932-4490, [...] , David Orlicky https://orcid.org/0000-0002-0417-1400, Michael McClelland https://orcid.org/0000-0003-1788-9347, and Andres Vazquez-Torres https://orcid.org/0000-0002-6181-4185 andres.vazquez-torres@cuanschutz.edu+4 authors +2 authors fewerAuthors Info & Affiliations Editor’s summary...
Sexual dimorphism in skin immunity is mediated by an androgen-ILC2-dendritic cell axis
Research Article IMMUNOLOGY Liang Chi https://orcid.org/0000-0002-3769-4144 ybelkaid@niaid.nih.gov, Can Liu https://orcid.org/0000-0002-8411-3891, [...] , Inta Gribonika https://orcid.org/0000-0002-5694-1315, Julia Gschwend https://orcid.org/0000-0001-7212-4393, [...] , Dan Corral, Seong-Ji Han, Ai Ing Lim https://orcid.org/0000-0001-8834-3136, Claudia A. Rivera, Verena M. Link https://orcid.org/0000-0002-3207-312X, [...] , Alexandria C.
Sex differences in tissue immunity
Androgen signaling skews skin immunity toward reduced inflammation in male mice Franz Puttur and Clare M. LloydAuthors Info & Affiliations Get full access to this article View all available purchase options and get full access to this article. References and Notes 1 L. Chi et al., Science 10.1126/science.adk6200 (2024). 2 J. P. Hoffmann, J. A. Liu, K. Seddu, S. L. Klein, Immunity56, 2472 (2023). 3 S. L. Klein, K. L. Flanagan, Nat. Rev. Immunol.16, 626 (2016). 4 M. Oliva et al., Science369, eaba3066 (2020). 5 X.
Pseudo-nanostructure and trapped-hole release induce high thermoelectric performance in PbTe
Research Article THERMOELECTRICS Baohai Jia https://orcid.org/0009-0008-5040-6654, Di Wu https://orcid.org/0000-0002-3467-819X, [...] , Lin Xie https://orcid.org/0000-0002-0332-0558, Wu Wang, [...] , Tian Yu, Shangyang Li, Yan Wang https://orcid.org/0000-0002-4554-8139, Yanjun Xu https://orcid.org/0009-0005-2261-1499, Binbin Jiang https://orcid.org/0000-0001-5337-8945, [...] , Zhiquan Chen https://orcid.org/0000-0002-9518-7837, Yuxiang Weng https://orcid.org/0000-0003-0423-2266, and Jiaqing...
Removal of Pseudomonas type IV pili by a small RNA virus
Research Article BACTERIOPHAGE Jirapat Thongchol https://orcid.org/0000-0003-1212-5751, Zihao Yu https://orcid.org/0000-0001-5431-2075, [...] , Laith Harb https://orcid.org/0000-0001-8914-5764, Yiruo Lin, [...] , Matthias Koch https://orcid.org/0000-0003-4408-9900, Matthew Theodore https://orcid.org/0000-0003-0625-7141, Utkarsh Narsaria, Joshua Shaevitz https://orcid.org/0000-0001-8809-4723, Zemer Gitai https://orcid.org/0000-0003-4081-6699, [...] , Yinghao Wu, Junjie Zhang...
In Other Journals
Primate Playtime Playful even when hungry Ekeoma Uzogara Chimpanzees at play in Kibale Forest Reserve in Uganda PHOTO: BLICKWINKEL/ALAMY STOCK PHOTO Open in viewer Social play between parents and offspring well into adulthood is beneficial for learning and cognitive and social development in humans. Our close primate relatives, wild chimpanzees, also engage in regular play, but may be constrained by ecological factors such as food scarcity. Sabbi et al.
Intelligent textiles are looking bright
AAAS login provides access to Science for AAAS Members, and access to other journals in the Science family to users who have purchased individual subscriptions. Download and print this article for your personal scholarly, research, and educational use. Buy a single issue of Science for just $15 USD.
Digitizing nature
The reviewer is at Sustainability in the Digital Age, Montréal, QC, Canada The reviewer is at Department of Geography, Planning and Environment, Concordia University, Montréal, QC, Canada The reviewer is at Future Earth Canada Hub, Montréal, QC, Canada
Research beneficiaries speak
Letter NextGen Voices Qian Ye yeqian7059@126.com, Yuzhou Gao gaoyuzhou7@163.com, [...] , Rishi Jai Patel ripatel@sas.upenn.edu, Bo Cao bocao@vip.qq.com, [...] , Aikang Li 17akli@stu.edu.cn, Jackson Powell jrp24@sas.upenn.edu, Yifei Cai cyf@caf.ac.cn, Isabel Marín-Beltrán imbeltran@ualg.pt, Zecheng Tao zecheng_tao@sjtu.edu.cn, [...] , Maryam Ejaz ejaz.m@live.unic.ac.cy, Syed S.
How Indigenous communities in New Zealand are protecting their data
Tahu Kukutai https://orcid.org/0000-0001-5080-2296Authors Info & Affiliations Concerns about the ethical use of data, privacy, and data harms are front of mind in many jurisdictions as regulators move to impose tighter controls on data privacy and protection, and the use of artificial intelligence (AI).
Dynamics of magnetization at infinite temperature in a Heisenberg spin chain
Research Article QUANTUM SIMULATION E. Rosenberg https://orcid.org/0000-0001-5889-8480, T. I. Andersen, [...] , R. Samajdar, A. Petukhov, [...] , J. C. Hoke, D. Abanin https://orcid.org/0000-0002-2461-0271, A. Bengtsson https://orcid.org/0000-0001-5264-4025, I. K. Drozdov, C. Erickson, [...] , P. V. Klimov, X. Mi https://orcid.org/0000-0003-0507-0211, A. Morvan https://orcid.org/0000-0002-9515-6184, M. Neeley https://orcid.org/0000-0002-5548-0051, C. Neill https://orcid.org/0000-0002-6563-3568, R. Acharya, R.
Regulating advanced artificial agents
Policy Forum Artificial Intelligence Governance frameworks should address the prospect of AI systems that cannot be safely tested Michael K. Cohen mkcohen@berkeley.edu, Noam Kolt, [...] , Yoshua Bengio, Gillian K.
Epithelial cells crowded out in asthma
Perspective Medicine Bronchoconstriction causes epithelial cell extrusion that promotes airway inflammation Jeffrey M. Drazen and Jeffrey J. Fredberg jjf@harvard.eduAuthors Info & Affiliations Abstract Reports of what were known at that time as “asthmatic fits” can be traced back millennia (1, 2), but a mechanistic understanding of the basis for what are now called asthma exacerbations remains incomplete.
‘Hydrovoltaics’ tap energy from ubiquitous moisture
When evaporation cools its head (blue in a thermal image), a “drinking bird” toy oscillates and generates energy. PHOTO: H. WU ET AL., CELL PRESS (2024) 10.1016/J.DEVICE.2024.100318 Open in viewer Sunlight and wind are the fastest growing energy sources on the planet. Now imagine drawing power from a third, even more plentiful green source: moisture in the air.
Don’t bury Mexico’s biodiversity capacity
Rodrigo A. Medellin medellin@ecologia.unam.mx and Jorge Soberón jsoberon@ku.eduAuthors Info & Affiliations In a world where biodiversity is on the line on many fronts—from armed conflict to pandemics to climate change—defending institutions that have effectively managed it is paramount. In the global effort to protect biodiversity, Mexico has been at the forefront.
Automated innovation and impact
Essay Innovation William Wasswa wwasswa@must.ac.ugAuthors Info & Affiliations In 2015, my grandmother succumbed to cervical cancer, which was linked to a late-stage diagnosis. This incident puzzled me because she had previously undergone cervical cancer screening, and the results had turned out to be negative.
Assessing the health burden from air pollution
Perspective Epidemiology A broader approach to assessing the burden of disease from air pollution is required Torben Sigsgaard ts@ph.au.dk and Barbara Hoffmann ts@ph.au.dkAuthors Info & Affiliations Human health is affected by air pollution, causing cardiometabolic, respiratory, and neurological disease and increased mortality.
Bronchoconstriction damages airway epithelia by crowding-induced excess cell extrusion
Research Article ASTHMA Dustin C. Bagley https://orcid.org/0000-0002-0450-3727, Tobias Russell https://orcid.org/0000-0001-7206-9312, [...] , Elena Ortiz-Zapater https://orcid.org/0000-0002-7437-4772, Sally Stinson, [...] , Kristina Fox https://orcid.org/0000-0001-6915-8904, Polly F.
Planting a chemical flag on antigens
Essay Innovation Aditya M. Kunjapur kunjapur@udel.eduAuthors Info & Affiliations Bacterial infections are a common cause of death across the globe and are an increasing threat as the prevalence of antibiotic resistance rises. Vaccines directed against bacterial pathogens prevent the spread of disease without the need for antibiotics and have an estimated global market size of 39.6 billion USD by 2030, with a compound annual growth rate of 7.7% (1).
Molecularly thin, two-dimensional all-organic perovskites
Research Article PEROVSKITES Hwa Seob Choi https://orcid.org/0000-0003-2964-761X, Jun Lin https://orcid.org/0000-0001-6209-1452, [...] , Gang Wang https://orcid.org/0009-0001-3052-2745, Walter P. D.
Apoptotic cell identity induces distinct functional responses to IL-4 in efferocytic macrophages
Research Article INNATE IMMUNITY Imke Liebold https://orcid.org/0000-0002-9708-4735, Amirah Al Jawazneh https://orcid.org/0000-0002-0327-2832, [...] , Christian Casar https://orcid.org/0000-0002-8624-1045, Clarissa Lanzloth, [...] , Stephanie Leyk https://orcid.org/0009-0007-4600-3214, Madeleine Hamley, Milagros N. Wong https://orcid.org/0009-0008-6372-7094, Dominik Kylies https://orcid.org/0009-0005-8801-0354, Stefanie K.
Lifelong persistence of nuclear RNAs in the mouse brain
Research Article CELLULAR NEUROSCIENCE Sara Zocher https://orcid.org/0000-0001-8211-5490, Asako McCloskey https://orcid.org/0009-0007-7606-187X, [...] , Anne Karasinsky, Roberta Schulte, [...] , Ulrike Friedrich https://orcid.org/0000-0001-7295-4549, Mathias Lesche https://orcid.org/0000-0002-3274-7163, Nicole Rund, Fred H. Gage https://orcid.org/0000-0002-0938-4106, Martin W.
Edible electronics to treat the brain
Essay Innovation Khalil Ramadi kramadi@nyu.eduAuthors Info & Affiliations If you stroll by the Hershey’s chocolate store in Times Square, you may be very tempted to enter. The smell of chocolate permeates the air, driven by exhaust fans that pump air onto the sidewalk. A similar urge might strike if you walk by your neighborhood bakery. Such is the power of neuromodulation. We are constantly exposed to external stimuli that activate innate and learned neural circuits that drive behavior.
Roger Guillemin (1924-2024)
Perspective Retrospective Father of neuroendocrinology Catherine Rivier crivier@salk.eduAuthors Info & Affiliations Roger Guillemin, founder of the field of neuroendocrinology, died on 21 February at the age of 100. Guillemin studied the interactions between hormones and the brain and the mechanisms through which such hormones control basic functions such as growth, reproduction, and the handling of stress.
Exceptionally long-lived nuclear RNAs
Perspective Molecular Biology RNA labeled in young mice is detected 2 years later in adult mouse brains Jeanne Lawrence jeanne.lawrence@umassmed.edu and Lisa HallAuthors Info & Affiliations Abstract RNA has come a long way from a simple “messenger” or “translator” of canonical genic information during the production of proteins. A plethora of new types of noncoding RNAs have been discovered, including thousands of long noncoding RNAs (lncRNAs), many of which have no identified functions (1, 2).
Epithelial cells crowded out in asthma
Perspective Medicine Bronchoconstriction causes epithelial cell extrusion that promotes airway inflammation Jeffrey M. Drazen and Jeffrey J. Fredberg Authors Info & Affiliations Abstract Reports of what were known at that time as “asthmatic fits” can be traced back millennia (1, 2), but a mechanistic understanding of the basis for what are now called asthma exacerbations remains incomplete.
Lifestyle and demographic associations with 47 inflammatory and vascular stress biomarkers in 9876 blood donors - Communications Medicine
|
Abstract The emerging use of biomarkers in research and tailored care introduces a need for information about the association between biomarkers and basic demographics and lifestyle factors revealing expectable concentrations in healthy individuals while considering general demographic differences. A selection of 47 biomarkers, including markers of inflammation and vascular stress, were measured in plasma samples from 9876 Danish Blood Donor Study participants.
By Bertram Kjerulff, Joseph Dowsett, Rikke Louise Jacobsen, Josephine Gladov, Agnete Troen Lundgaard, Karina Banasik, David Westergaard, Khoa Manh Dinh, Kathrine Agergård Kaspersen, Michael C Schwinn, Anders Juul, Carsten Bøcker Pedersen, Clive Eric Sabel, Henriette Svarre Nielsen, Maria Didriksen, Mette Nyegaard, Niels Grarup, Pär Johansson, Ruth Frikke-Schmidt, Sanne Schou Berger, Søren Brunak, Søren Jacobsen, Thomas Hansen, Torben Frøstrup Hansen, Torben Sigsgaard, Mie Topholm Bruun, Henrik Hjalgrim, Klaus Rostgaard, Ole Birger Pedersen
|
Nature
Verified
ATR blocks telomerase from converting DNA breaks into telomeres
Research Article MOLECULAR BIOLOGY Charles G. Kinzig https://orcid.org/0000-0002-4592-7411, George Zakusilo, [...] , Kaori K. Takai, Logan R.
Humans are biocultural, science should be too
Agustín Fuentes https://orcid.org/0000-0003-0955-8214Authors Info & Affiliations COVID-19 is restructuring societies. Loneliness is a global health threat. Large language models are outputting biased health care information, and human–artificial intelligence (AI) interfaces are reshaping how we live. For most humans, technology, biology, and society are hopelessly entangled. Are the sciences prepared to tackle the contemporary human experience?
Dampness, mould, onset and remission of adult respiratory symptoms, asthma and rhinitis
Juan Wang, Mihkel Pindus, Christer Janson, Torben Sigsgaard, Jeong-Lim Kim, Mathias Holm, Johan Sommar, Hans Orru, Thorarinn Gislason, Ane Johannessen, Randi J. Bertelsen, Dan Norbäck European Respiratory Journal 2019 53: 1801921; DOI: 10.1183/13993003.01921-2018 Abstract Study question Is dampness and indoor mould associated with onset and remission of respiratory symptoms, asthma and rhinitis among adults?
Dampness, mould, onset and remission of adult respiratory symptoms, asthma and rhinitis
Juan Wang, Mihkel Pindus, Christer Janson, Torben Sigsgaard, Jeong-Lim Kim, Mathias Holm, Johan Sommar, Hans Orru, Thorarinn Gislason, Ane Johannessen, Randi J. Bertelsen, Dan Norbäck European Respiratory Journal 2019; DOI: 10.1183/13993003.01921-2018 Abstract The question addressed by the study Is dampness and indoor mould associated with onset and remission of respiratory symptoms, asthma and rhinitis among adults?
The effect of organic dust exposure on long-term change in lung function: a systematic review and meta-analysis
Lung function is a predictor of morbidity and mortality, and the chronic nature of lung function decline allows for preventive initiatives. Proinflammatory constituents of organic dust are considered a possible cause of compromised respiratory health. The aim of this systematic review was to reveal the impact of organic dust exposure on long-term change in lung function.
The effect of organic dust exposure on long-term change in lung function: a systematic review and meta-analysis
Lung function is a predictor of morbidity and mortality, and the chronic nature of lung function decline allows for preventive initiatives. Proinflammatory constituents of organic dust are considered a possible cause of compromised respiratory health. The aim of this systematic review was to reveal the impact of organic dust exposure on long-term change in lung function.
A Comparison between Temperature-Controlled Laminar Airflow Device and a Room Air-Cleaner in Reducing Exposure to Particles While Asleep
People spend approximately one third of their life sleeping. Exposure to pollutants in the sleep environment often leads to a variety of adverse health effects, such as development and exacerbation of asthma. Avoiding exposure to these pollutants by providing a sufficient air quality in the sleep environment might be a feasible method to alleviate these health symptoms. We performed full-scale laboratory measurements using a thermal manikin positioned on an experimental bed.
The effect of organic dust exposure on change in lung function - A systematic review
AbstractBackground: Lung function is a predictor of morbidity and mortality and the chronic nature of lung function decline facilitates preventive initiatives. Pro-inflammatory microbial constituents of organic dust are considered a cause of respiratory disease.
Exposure to traffic pollution is related to daytime sleepiness and habitual snoring: Results from the RHINE study
Exposure to traffic pollution is related to daytime sleepiness and habitual snoring: Results from the RHINE study Ane Johannessen, Randi Bertelsen, Francisco Gomez Real, Torben Sigsgaard, Karl A. Franklin, Eva Lindberg, Christer Janson, Erna Sif Arnardottir, Johan Hellgren, Bryndis Benediktsdottir, Bertil Forsberg, Thorarinn Gislason European Respiratory Journal Sep 2016, 48 (suppl 60) PA4922; DOI: 10.1183/13993003.congress-2016.PA4922
Visualization and analysis of gene expression in tissue sections by spatial transcriptomics
Patrik L. Ståhl, Fredrik Salmén, [...] , Sanja Vickovic, Anna Lundmark, [...] , José Fernández Navarro, Jens Magnusson, Stefania Giacomello, Michaela Asp, Jakub O.
Predicting Elections: Child's Play!
1 Plato, The Republic, B. Jowett, Transl. (Collier, New York, 1901). 2 F. L. Schmidt, J. E. Hunter, Psychol. Bull.124, 262 (1998). 3 D. K. Simonton, in Advances in Psychological Research, S. P. Shohov, Ed. (Nova Science, Hauppauge, NY, 2002), vol. 14, pp. 143–153.
Avian H5N1 Influenza in Cats
Information & Authors Information Published In Science Volume 306 | Issue 5694 8 October 2004 Copyright American Association for the Advancement of Science. Article versions You are viewing the most recent version of this article. Submission history Received: 2 July 2004 Accepted: 6 August 2004 Published in print: 8 October 2004 Permissions Request permissions for this article. Notes Supporting Online Material www.sciencemag.org/cgi/content/full/1102287/DC1 Fig.
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Torben
Contact Torben, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack