INTRODUCTION Waldenström macroglobulinaemia (WM) is characterized by clonal expansion of mature B cells in the bone marrow (BM) and the presence of an immunoglobulin M (IgM) monoclonal protein.1 Although the BM is the primary site of disease, patients with WM may also present with extra-medullary disease, including both nodal and extra-nodal manifestations.2, 3 In other indolent B-cell lymphomas, the nodal tumour burden is a predictor of adverse outcomes and an indicator of a need for...
