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Abstract Biofilms are a cause of chronic, non-healing infections. Staphylococcus aureus is a proficient biofilm forming pathogen commonly isolated from prosthetic joint infections that develop following primary arthroplasty. Extracellular adhesion protein (Eap), previously characterized in planktonic or non-biofilm populations as being an adhesin and immune evasion factor, was recently identified in the exoproteome of S. aureus biofilms.
by Tyler Scherr, UNeMed Gus Wang, Ph.D., an associate professor in the UNMC Department of Pathology and Microbiology and a world-leading expert on antimicrobial peptides, has published a field-altering discovery in the Proceedings of the National Academy of Sciences of the United States, widely regarded as one of the most prestigious academic journals.
The incidence of methicillin-resistant Staphylococcus aureus (MRSA) pneumonia in otherwise healthy individuals is increasing. To investigate the mechanism underlying the epidemiological success of predominant community-associated (CA)-MRSA strains, we examined their fitness traits during the initial interaction between bacteria and the host occurring in the lower airway.
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