English Gastrointestinal adverse effects of humanized monoclonal antibodies against vascular endothelial growth factor A activity are among the most common; however, there are no reported clinical cases of ulcerative colitis secondary to the use of this drug. We present the case of a 72-year-old female patient diagnosed with ovarian cancer who was receiving palliative chemotherapy with oxyplatin, cisplatin, and bevacizumab and presented with symptoms of hematochezia.