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Loading metrics Open Access Perspective Perspective Perspectives are commissioned from an expert and discuss the clinical practice or public health implications of a published study. The original publication must be freely available online.
Recent prevalence estimates suggest that at least 33.5 million persons are affected by atrial fibrillation (AF).1 Catheter ablation is increasingly offered to relieve AF-related symptoms,2–4 based on evidence illustrating its efficacy compared with antiarrhythmic drug therapy.5–9 There is less evidence supporting AF ablation in persistent AF, although small studies suggest better maintenance of sinus rhythm.
AbstractCatheter ablation is increasingly offered to patients who suffer from symptoms due to atrial fibrillation (AF), based on a growing body of evidence illustrating its efficacy compared with antiarrhythmic drug therapy. Approximately one-third of AF ablation procedures are currently performed in patients with persistent or long-standing persistent AF. Here, we review the available information to guide catheter ablation in these more chronic forms of AF.
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