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Articles by Ulf Simonsen
BCPT 2025 Prizes and Awards
Data Availability Statement Data sharing is not applicable to this article as no datasets were generated or analysed during the current study. References 1, , and , “Acetaminophen in Pregnancy: A Population-Level Drug-Utilization Study of Prescription-Based Acetaminophen Use Among Pregnant Women in Denmark From 2001 to 2023,” Basic & Clinical Pharmacology & Toxicology 136, no. 6 (2025): e70048, https://doi.org/10.1111/bcpt.70048.
Cyanide Beyond Toxicity: A Systematic Review of Its Effects on Vascular Function
1 Introduction Cyanide is traditionally recognized as an environmental toxin, poison and cytotoxic agent. The term cyanide (CN) encompasses both the cyanide anion (CN−) and undissociated hydrogen cyanide (HCN). Cyanide is classified as a weak acid (pKa = 9.22, 25°C). At physiological pH, cyanide predominantly exists as HCN, which is the volatile and more toxic form.
Blood Pressure-Lowering Effects of Aldosterone Synthase Inhibitors-A Systematic Review
Poorly controlled hypertension results in cardiovascular diseases. Excess production of the hormone aldosterone worsens hypertension and organ damage. Aldosterone synthase inhibitors (ASIs) constitute a novel group of medications, and five different ASIs have now been tested in clinical trials.
Blood Pressure-Lowering Effects of Aldosterone Synthase Inhibitors-A Systematic Review
Poorly controlled hypertension results in cardiovascular diseases. Excess production of the hormone aldosterone worsens hypertension and organ damage. Aldosterone synthase inhibitors (ASIs) constitute a novel group of medications, and five different ASIs have now been tested in clinical trials.
Contractions Induced in Human Pulmonary Arteries by a H2S Donor, GYY 4137, Are Inhibited by Low-Frequency (20 kHz) Ultrasound
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Welcome to Basic & Clinical Pharmacology & Toxicology 2024
ANNOUNCEMENT Welcome to Basic & Clinical Pharmacology & Toxicology 2024 Ulf Simonsen, Corresponding Author Ulf Simonsen Department of Biomedicine, Aarhus University, Aarhus, Denmark Correspondence Ulf Simonsen, Department of Biomedicine, Aarhus University, Aarhus, Denmark.
BCPT 2023 policy for experimental and clinical studies
Corresponding Author Jens Lykkesfeldt Section of Preclinical Disease Biology, Department of Veterinary and Animal Sciences, University of Copenhagen, Copenhagen, Denmark Correspondence Jens Lykkesfeldt, Section of Preclinical Disease Biology, Department of Veterinary and Animal Sciences, University of Copenhagen, Ridebanevej 9, 1870 Frederiksberg C, Denmark. Email: jopl@sund.ku.dk Search for more papers by this author
Charting a New Course: A Vision for the Future as Editors‐in‐Chief
EDITORIAL Charting a New Course: A Vision for the Future as Editors-in-Chief Ulf Simonsen, Corresponding Author Ulf Simonsen Department of Biomedicine, Aarhus University, Denmark Correspondence Correspondent author: Ulf Simonsen, MD, Ph.D., Department of Biomedicine, Pulmonary and Cardiovascular Pharmacology, Aarhus University, Ole Worms Allé 4, 8000 Aarhus C, Denmark.
A Systematic Review of the Effect of Vericiguat on Patients with Heart Failure
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessReview by 1, 2, 1, 2 and 1,2,* 1 Department of Biomedicine, The Faculty of Health, Aarhus University, Ole Worms Allé 4, 8000 Aarhus, Denmark 2 Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany * Author to whom correspondence should be addressed. Int. J. Mol. Sci.
Nitric Oxide Attenuates Arterial Pulse Wave Reflection in a Vasodilator Responding Pulmonary Arterial Hypertension Patient
Pulmonary arterial hypertension (PAH) is characterized by distal vasoconstriction, vascular remodeling, microvascular injury, and thrombosis leading to increased pulmonary vascular resistance (PVR) and elevated mean pulmonary arterial pressure (PAPm).
Modulation of Dopaminergic Pathways to Treat Erectile Dysfunction
Antipsychotics and erectile function Most antipsychotic drugs bind to and antagonize the effect of dopamine at dopamine D2 receptors, for example haloperidol. Therefore, older anti-psychotic drugs are often associated with decreased erection and anorgasmia in 30–60% of the patients, while newer anti-psychotics appear to have lower incidence of sexual dysfunction 5, 62.
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