DERMATOLOGY Adult dermatology Epidemiology Dermatopathology PUBLIC HEALTH The Australian Centre of Excellence in Melanoma Imaging and Diagnosis cohort study will establish the largest, world-first, prospectively collected standardised three-dimensional total body skin surface image data collection. Comprehensive collection of data on personal, immunological, genetic and clinical risk factors. Large sample size, recruited across 15 metropolitan and regional sites in three Australian eastern states.