For this study, we selected two strains of mice that differ in their susceptibility to S. aureus infection16,17. Whereas A/J mice are very vulnerable to S. aureus, resulting in a significantly increased bacterial growth in the kidneys (Fig. 1a) and liver (Fig. 1b) and fatal infection outcome (Fig. 1c), C57BL/6 mice exhibit greater resistance to S. aureus and were capable to significantly restrict bacterial growth in the kidneys (Fig. 1a) and liver (Fig. 1b) with all mice surviving (Fig. 1c).
