The aim of this paper was to determine whether the use of preoperative antibiotics improves surgical outcomes following oroantral communication (OAC) closure. A single-centre, retrospective study was conducted on all OAC repair procedures over a 24-month period assessing a number of datapoints including the site of OAC occurrence, time to repair, local anaesthetic or general anaesthetic, and any complications noted. Patient follow-up was up to 3 months post-operative OAC closure.