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1 Introduction Natural Killer (NK) cells are innate cytotoxic lymphocytes able to recognise and eliminate cells infected with viruses, as well as tumour cells, thereby constituting an integral part of the innate immune system. NK cells detect target cells with their germline-encoded receptors and do not require prior priming. Their activation depends on a complex homeostatic balance of activating and inhibitory signals [1, 2].
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