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Amorphous materials exhibit complex material properties with strongly nonlinear behaviors. Below a yield stress they behave as plastic solids, while they start to yield above a critical stress Σc. A key quantity controlling plasticity which is, however, hard to measure is the density P(x) of weak spots, where x is the additional stress required for local plastic failure. In the thermodynamic limit P(x) ∼ xθ is singular at x = 0 in the solid phase below the yield stress Σc.
Abstract HIV-1 is a rapidly evolving virus able to evade host immunity through rapid adaptation during chronic infection. The HIV-1 group M has diversified since its zoonosis into several subtypes at a rate of the order of 10^-3 changes per site per year. This rate varies between different parts of the genome and its inference is sensitive to the time scale and diversity spanned by the sequence data used.
Abstract A novel coronavirus (SARS-CoV-2) first detected in Wuhan, China, has spread rapidly since December 2019, causing over 45,000 PCR confirmed infections and more than 1,000 fatalities (as of Feb 12, 2020). Imported cases and small transmission clusters have been reported globally. Early data suggest the virus transmits readily and a pandemic cannot be ruled out.
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